Recovery of antigen-specific T cell responses from dogs infected with Leishmania (L.) infantum by use of vaccine associated TLR-agonist adjuvant

Visceral leishmaniasis (VL), caused by infection with the obligate intracellular protozoan parasite Leishmania infantum, is a fatal disease of dogs and humans. Protection against VL requires a T helper 1 (Th1) skewed CD4(+) T response, but despite this knowledge, there are currently no approved-to-m...

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Détails bibliographiques
Publié dans:Vaccine
Auteurs principaux: Schaut, Robert G., Grinnage-Pulley, Tara L., Esch, Kevin J., Toepp, Angela J., Duthie, Malcolm S., Howard, Randall F., Reed, Steven G., Petersen, Christine A.
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053902/
https://ncbi.nlm.nih.gov/pubmed/27665354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.09.016
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