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Vaccination with a ΔnorD ΔznuA Brucella abortus mutant confers potent protection against virulent challenge

There remains a need for an improved livestock vaccine for brucellosis since conventional vaccines are only ~70% efficacious, making some vaccinated animals susceptible to Brucella infections. To address this void, a vaccine capable of evoking protective immunity while still being sufficiently atten...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine
Hauptverfasser: Yang, Xinghong, Clapp, Beata, Thornburg, Theresa, Hoffman, Carol, Pascual, David W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053898/
https://ncbi.nlm.nih.gov/pubmed/27639282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2016.09.004
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