Persisting PET-CT lesion activity and M. tuberculosis mRNA after pulmonary tuberculosis cure

The absence of a gold standard to determine when antibiotics have induced sterilizing cure confounds the development of new approaches to treat pulmonary tuberculosis (PTB). We detected PET-CT imaging response patterns consistent with active disease along with the presence of Mycobacterium tuberculo...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Malherbe, Stephanus T., Shenai, Shubhada, Ronacher, Katharina, Loxton, Andre G., Dolganov, Gregory, Kriel, Magdalena, Van, Tran, Chen, Ray Y., Warwick, James, Via, Laura E., Song, Taeksun, Lee, Myungsun, Schoolnik, Gary, Tromp, Gerard, Alland, David, Barry, Clifton E., Winter, Jill, Walzl, Gerhard
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053881/
https://ncbi.nlm.nih.gov/pubmed/27595324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.4177
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