A reciprocal regulatory circuit between CD44 and FGFR2 via c-myc controls gastric cancer cell growth

Despite their suggested importance, the mechanistic roles of FGFR2 and gastric cancer stem cell (GCSC) marker CD44 remain unclear. We investigated cross talk between CD44 and FGFR2. FGFR2 and CD44 positively regulate each other's expression. While FGFR2 suppresses c-Myc transcription, CD44 acti...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Park, Jihyun, Kim, Sun Young, Kim, Ha-Jung, Kim, Kyoung-Mee, Choi, Eun Young, Kang, Myung-Soo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053754/
https://ncbi.nlm.nih.gov/pubmed/27107424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8764
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