Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma

BACKGROUND: Therapeutic management of Locally Advanced Rectal Cancer (LARC) involves pre-operative chemoradiotherapy (pCRT) followed by surgery. However, after pCRT the complete pathological response is approximately 20%, whereas in 20 to 40% of patients the response is poor or absent. METHODS: Canc...

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Veröffentlicht in:Oncotarget
Hauptverfasser: D'Angelo, Edoardo, Fassan, Matteo, Maretto, Isacco, Pucciarelli, Salvatore, Zanon, Carlo, Digito, Maura, Rugge, Massimo, Nitti, Donato, Agostini, Marco
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053752/
https://ncbi.nlm.nih.gov/pubmed/27081702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8725
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