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Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1

Alterations of histone methylation dynamically regulated by methyltransferases and demethylases are frequently found in human cancers. Here, we showed that expression of lysine demethylase 2A (KDM2A) is markedly increased in human breast cancer and its overexpression is associated with tumor progres...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chen, Jing-Yi, Li, Chien-Feng, Chu, Pei-Yi, Lai, You-Syuan, Chen, Chung-Hsing, Jiang, Shih Sheng, Hou, Ming-Feng, Hung, Wen-Chun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053681/
https://ncbi.nlm.nih.gov/pubmed/27029061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8381
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