Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

We recently introduced CDK5 as target in HCC, regulating DNA damage response. Based on this and on our previous knowledge about vascular effects of CDK5, we investigated the role of CDK5 in angiogenesis in HCC, one of the most vascularized tumors. We put a special focus on the transcription factor H...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Herzog, Julia, Ehrlich, Sandra M., Pfitzer, Lisa, Liebl, Johanna, Fröhlich, Thomas, Arnold, Georg J., Mikulits, Wolfgang, Haider, Christine, Vollmar, Angelika M., Zahler, Stefan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053636/
https://ncbi.nlm.nih.gov/pubmed/27027353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8342
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