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Extracellular-signal regulated kinase 8 of Trypanosoma brucei uniquely phosphorylates its proliferating cell nuclear antigen homolog and reveals exploitable properties

The Trypanosoma brucei subspecies T. brucei gambiense and T. brucei rhodesiense are vector-borne pathogens that cause sleeping sickness also known as Human African Trypanosomiasis (HAT), which is fatal if left untreated. The drugs that treat HAT are ineffective and cause toxic side effects. One stra...

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Foilsithe in:Cell Cycle
Main Authors: Valenciano, Ana L., Knudsen, Giselle M., Mackey, Zachary B.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053586/
https://ncbi.nlm.nih.gov/pubmed/27589575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1222340
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