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Why is an energy metabolic defect the common outcome in BMFS?

Inherited bone marrow failure syndromes (BMFS) are rare, distressing, inherited blood disorders of children. Although the genetic origin of these pathologies involves genes with different functions, all are associated with progressive haematopoietic impairment and an excessive risk of malignancies....

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Foilsithe in:Cell Cycle
Main Authors: Degan, Paolo, Ravera, Silvia, Cappelli, Enrico
Formáid: Artigo
Teanga:Inglês
Foilsithe: Taylor & Francis 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053575/
https://ncbi.nlm.nih.gov/pubmed/27579499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1218103
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