Enlargement of the Axial Length and Altered Ultrastructural Features of the Sclera in a Mutant Lumican Transgenic Mouse Model

Lumican (LUM) is a candidate gene for myopia in the MYP3 locus. In this study, a mutant lumican (L199P) transgenic mouse model was established to investigate the axial length changes and ultrastructural features of the sclera. The mouse model was established by pronuclear microinjection. Transgenic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Song, Yanzheng, Zhang, Fengju, Zhao, Yanyan, Sun, Mingshen, Tao, Jun, Liang, Yanchuang, Ma, Ling, Yu, Yanqiu, Wang, Jianhua, Hao, Junfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053428/
https://ncbi.nlm.nih.gov/pubmed/27711221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0163165
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