Bosentan and macitentan prevent the endothelial-to-mesenchymal transition (EndoMT) in systemic sclerosis: in vitro study

BACKGROUND: Systemic sclerosis (SSc) is characterized by early vascular abnormalities and subsequent fibroblast activation to myofibroblasts, leading to fibrosis. Recently, endothelial-to-mesenchymal transition (EndoMT), a complex biological process in which endothelial cells lose their specific mar...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Corallo, Claudio, Cutolo, Maurizio, Kahaleh, Bashar, Pecetti, Gianluca, Montella, Antonio, Chirico, Chiara, Soldano, Stefano, Nuti, Ranuccio, Giordano, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053154/
https://ncbi.nlm.nih.gov/pubmed/27716320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1122-y
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