IL-3 promotes the development of experimental autoimmune encephalitis

Little is known about the role of IL-3 in multiple sclerosis (MS) in humans and in experimental autoimmune encephalomyelitis (EAE). Using myelin oligodendrocyte glycoprotein (MOG) peptide–induced EAE, we show that CD4(+) T cells are the main source of IL-3 and that cerebral IL-3 expression correlate...

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Vydáno v:JCI Insight
Hlavní autoři: Renner, Kerstin, Hellerbrand, Sonja, Hermann, Fabian, Riedhammer, Christine, Talke, Yvonne, Schiechl, Gabriela, Gomez, Manuel Rodriguez, Kutzi, Simone, Halbritter, Dagmar, Goebel, Nicole, Brühl, Hilke, Weissert, Robert, Mack, Matthias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053150/
https://ncbi.nlm.nih.gov/pubmed/27734026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87157
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