Basophils inhibit proliferation of CD4(+) T cells in autologous and allogeneic mixed lymphocyte reactions and limit disease activity in a murine model of graft versus host disease

Basophils are known to modulate the phenotype of CD4(+) T cells and to enhance T helper type 2 responses in vitro and in vivo. In this study, we demonstrate that murine basophils inhibit proliferation of CD4(+) T cells in autologous and allogeneic mixed lymphocyte reactions. The inhibition is indepe...

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Publicado en:Immunology
Autores principales: Hermann, Fabian J, Rodriguez Gomez, Manuel, Doser, Kristina, Edinger, Matthias, Hoffmann, Petra, Schiechl, Gabriela, Talke, Yvonne, Göbel, Nicole, Schmidbauer, Kathrin, Syed, Shahzad N, Brühl, Hilke, Mack, Matthias
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Original Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4427385/
https://ncbi.nlm.nih.gov/pubmed/25545131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12436
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