NK cell activating receptor ligand expression in lymphangioleiomyomatosis is associated with lung function decline

Lymphangioleiomyomatosis (LAM) is a rare lung disease of women that leads to progressive cyst formation and accelerated loss of pulmonary function. Neoplastic smooth muscle cells from an unknown source metastasize to the lung and drive destructive remodeling. Given the role of NK cells in immune sur...

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Pubblicato in:JCI Insight
Autori principali: Osterburg, Andrew R., Nelson, Rebecca L., Yaniv, Benyamin Z., Foot, Rachel, Donica, Walter R.F., Nashu, Madison A., Liu, Huan, Wikenheiser-Brokamp, Kathryn A., Moss, Joel, Gupta, Nishant, McCormack, Francis X., Borchers, Michael T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053147/
https://ncbi.nlm.nih.gov/pubmed/27734028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.87270
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