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Activation Mechanism of the Bacteroides fragilis Cysteine Peptidase, Fragipain
Enterotoxigenic Bacteroides fragilis produces a secreted metalloprotease known as B. fragilis toxin (BFT), which contributes to anaerobic sepsis, colitis, and colonic malignancy in mouse models of disease. A C11 family cysteine protease, fragipain (Fpn), directly activates BFT in the B. fragilis cel...
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| Publicado en: | Biochemistry |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5053104/ https://ncbi.nlm.nih.gov/pubmed/27379832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.6b00546 |
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