Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice

BACKGROUND: Toxoplasma gondii is an opportunistic protozoan closely associated with AIDS and vertical transmission. T. gondii actin depolymerizing factor (TgADF) plays an important role in actin cytoskeleton remodeling, and it is required to invade host cells. TgADF was a promising vaccine candidate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:BMC Immunol
Prif Awduron: Liu, Zhuanzhuan, Yin, Litian, Li, Yaqing, Yuan, Fei, Zhang, Xiaofan, Ma, Jiazhi, Liu, Hongmei, Wang, Yanjuan, Zheng, Kuiyang, Cao, Jianping
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053087/
https://ncbi.nlm.nih.gov/pubmed/27716047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0173-9
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