Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice

BACKGROUND: Toxoplasma gondii is an opportunistic protozoan closely associated with AIDS and vertical transmission. T. gondii actin depolymerizing factor (TgADF) plays an important role in actin cytoskeleton remodeling, and it is required to invade host cells. TgADF was a promising vaccine candidate...

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Detalhes bibliográficos
Publicado no:BMC Immunol
Main Authors: Liu, Zhuanzhuan, Yin, Litian, Li, Yaqing, Yuan, Fei, Zhang, Xiaofan, Ma, Jiazhi, Liu, Hongmei, Wang, Yanjuan, Zheng, Kuiyang, Cao, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053087/
https://ncbi.nlm.nih.gov/pubmed/27716047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0173-9
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