Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice

BACKGROUND: Toxoplasma gondii is an opportunistic protozoan closely associated with AIDS and vertical transmission. T. gondii actin depolymerizing factor (TgADF) plays an important role in actin cytoskeleton remodeling, and it is required to invade host cells. TgADF was a promising vaccine candidate...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Immunol
Auteurs principaux: Liu, Zhuanzhuan, Yin, Litian, Li, Yaqing, Yuan, Fei, Zhang, Xiaofan, Ma, Jiazhi, Liu, Hongmei, Wang, Yanjuan, Zheng, Kuiyang, Cao, Jianping
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053087/
https://ncbi.nlm.nih.gov/pubmed/27716047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0173-9
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