Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice

BACKGROUND: Toxoplasma gondii is an opportunistic protozoan closely associated with AIDS and vertical transmission. T. gondii actin depolymerizing factor (TgADF) plays an important role in actin cytoskeleton remodeling, and it is required to invade host cells. TgADF was a promising vaccine candidate...

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Bibliografiska uppgifter
I publikationen:BMC Immunol
Huvudupphovsmän: Liu, Zhuanzhuan, Yin, Litian, Li, Yaqing, Yuan, Fei, Zhang, Xiaofan, Ma, Jiazhi, Liu, Hongmei, Wang, Yanjuan, Zheng, Kuiyang, Cao, Jianping
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053087/
https://ncbi.nlm.nih.gov/pubmed/27716047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12865-016-0173-9
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