Binding and transport of gangliosides by prosaposin.
Prosaposin, the precursor of saposins A, B, C, and D, which activate lysosomal hydrolysis of sphingolipids, exists in various tissues and body fluids and is especially abundant in the nervous system. Prosaposin and saposins A,B, C, and D formed stable complexes with 13 different gangliosides as meas...
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| Published in: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
National Academy of Sciences
1992
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50528/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1454804/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.23.11254 |
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