The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation

The liver is essential for the synthesis of plasma proteins and integration of lipid metabolism. While the role of transcriptional networks in these processes is increasingly understood, less is known about post-transcriptional control of gene expression by RNA-binding proteins (RBPs). Here, we show...

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Publicado en:Nat Commun
Main Authors: Mobin, Mehrpouya B., Gerstberger, Stefanie, Teupser, Daniel, Campana, Benedetta, Charisse, Klaus, Heim, Markus H., Manoharan, Muthiah, Tuschl, Thomas, Stoffel, Markus
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052685/
https://ncbi.nlm.nih.gov/pubmed/27665711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12848
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