The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation

The liver is essential for the synthesis of plasma proteins and integration of lipid metabolism. While the role of transcriptional networks in these processes is increasingly understood, less is known about post-transcriptional control of gene expression by RNA-binding proteins (RBPs). Here, we show...

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Vydáno v:Nat Commun
Hlavní autoři: Mobin, Mehrpouya B., Gerstberger, Stefanie, Teupser, Daniel, Campana, Benedetta, Charisse, Klaus, Heim, Markus H., Manoharan, Muthiah, Tuschl, Thomas, Stoffel, Markus
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052685/
https://ncbi.nlm.nih.gov/pubmed/27665711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12848
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