MicroRNA-155 influences B-cell function through PU.1 in rheumatoid arthritis

MicroRNA-155 (miR-155) is an important regulator of B cells in mice. B cells have a critical role in the pathogenesis of rheumatoid arthritis (RA). Here we show that miR-155 is highly expressed in peripheral blood B cells from RA patients compared with healthy individuals, particularly in the IgD(-)...

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Vydáno v:Nat Commun
Hlavní autoři: Alivernini, Stefano, Kurowska-Stolarska, Mariola, Tolusso, Barbara, Benvenuto, Roberta, Elmesmari, Aziza, Canestri, Silvia, Petricca, Luca, Mangoni, Antonella, Fedele, Anna Laura, Di Mario, Clara, Gigante, Maria Rita, Gremese, Elisa, McInnes, Iain B., Ferraccioli, Gianfranco
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052655/
https://ncbi.nlm.nih.gov/pubmed/27671860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12970
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