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A Novel Voltage Sensor in the Orthosteric Binding Site of the M2 Muscarinic Receptor
G protein-coupled receptors (GPCRs) mediate many signal transduction processes in the body. The discovery that these receptors are voltage-sensitive has changed our understanding of their behavior. The M2 muscarinic acetylcholine receptor (M2R) was found to exhibit depolarization-induced charge move...
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| Publicado no: | Biophys J |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5052511/ https://ncbi.nlm.nih.gov/pubmed/27705763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.08.035 |
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