Differential transcriptional regulation of hypoxia-inducible factor-1α by arsenite under normoxia and hypoxia: involvement of Nrf2

ABSTRACT: Arsenite (As(III)) is widely distributed in nature and can be found in water, food, and air. There is significant evidence that exposure to As(III) is associated with human cancers originated from liver, lung, skin, bladder, kidney, and prostate. Hypoxia plays a role in tumor growth and ag...

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Détails bibliographiques
Publié dans:J Mol Med (Berl)
Auteurs principaux: al Taleb, Zukaa, Petry, Andreas, Chi, Tabughang Franklin, Mennerich, Daniela, Görlach, Agnes, Dimova, Elitsa Y., Kietzmann, Thomas
Format: Artigo
Langue:Inglês
Publié: Springer Berlin Heidelberg 2016
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052318/
https://ncbi.nlm.nih.gov/pubmed/27286880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00109-016-1439-7
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