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Piperidine-based glycodendrons as protein N-glycan prosthetics

The generation of homogeneously glycosylated proteins is essential for defining glycoform-specific activity and improving protein-based therapeutics. We present a novel glycodendron prosthetic which can be site-selectively appended to recombinant proteins to create “N-glycosylated” glycoprotein mimi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Bioorg Med Chem
Egile Nagusiak: Hudak, Jason E., Belardi, Brian, Appel, Mason J., Solania, Angelo, Robinson, Peter V., Bertozzi, Carolyn R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5052108/
https://ncbi.nlm.nih.gov/pubmed/27283789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2016.05.050
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