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Combined integrated protocol/basket trial design for a first-in-human trial
BACKGROUND: Innovative trial designs are sought to streamline drug development in rare diseases. Basket- and integrated protocol designs are two of these new strategies and have been applied in a handful oncologic trials. We have taken the concept outside the realm of oncology and report about a fir...
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Publicado no: | Orphanet J Rare Dis |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050564/ https://ncbi.nlm.nih.gov/pubmed/27716293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13023-016-0494-z |
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