FAM134B, the Selective Autophagy Receptor for Endoplasmic Reticulum Turnover, Inhibits Replication of Ebola Virus Strains Makona and Mayinga

Selective autophagy of the endoplasmic reticulum (termed ER-phagy) is controlled by members of the FAM134 reticulon protein family. Here we used mouse embryonic fibroblasts from mice deficient in FAM134B to examine the role of the ER in replication of historic (Mayinga) or contemporary (Makona GCO7)...

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Udgivet i:J Infect Dis
Main Authors: Chiramel, Abhilash I., Dougherty, Jonathan D., Nair, Vinod, Robertson, Shelly J., Best, Sonja M.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Ebola Outbreak in West Africa
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050481/
https://ncbi.nlm.nih.gov/pubmed/27511895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw270
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