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Integrated analysis of microRNA and mRNA expression profiles highlights the complex and dynamic behavior of toosendanin-induced liver injury in mice

Triterpenoid Toosendanin (TSN) exhibits a plenty of pharmacological effects in human and great values in agriculture. However, the hepatotoxicity caused by TSN or Melia-family plants containing TSN used in traditional Chinese medicine has been reported, and the mechanisms of TSN-induced liver injury...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Lu, Xiaoyan, Ji, Cai, Tong, Wei, Lian, Xueping, Wu, Ying, Fan, Xiaohui, Gao, Yue
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050432/
https://ncbi.nlm.nih.gov/pubmed/27703232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34225
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