Two isoforms of TALDO1 generated by alternative translational initiation show differential nucleocytoplasmic distribution to regulate the global metabolic network

Transaldolase 1 (TALDO1) is a rate-limiting enzyme involved in the pentose phosphate pathway, which is traditionally thought to occur in the cytoplasm. In this study, we found that the gene TALDO1 has two translational initiation sites, generating two isoforms that differ by the presence of the firs...

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Udgivet i:Sci Rep
Main Authors: Moriyama, Tetsuji, Tanaka, Shu, Nakayama, Yasumune, Fukumoto, Masahiro, Tsujimura, Kenji, Yamada, Kohji, Bamba, Takeshi, Yoneda, Yoshihiro, Fukusaki, Eiichiro, Oka, Masahiro
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050407/
https://ncbi.nlm.nih.gov/pubmed/27703206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34648
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