Dissecting the Effect of Genetic Variation on the Hepatic Expression of Drug Disposition Genes across the Collaborative Cross Mouse Strains

A central challenge in pharmaceutical research is to investigate genetic variation in response to drugs. The Collaborative Cross (CC) mouse reference population is a promising model for pharmacogenomic studies because of its large amount of genetic variation, genetic reproducibility, and dense recom...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Nachshon, Aharon, Abu-Toamih Atamni, Hanifa J., Steuerman, Yael, Sheikh-Hamed, Roa'a, Dorman, Alexandra, Mott, Richard, Dohm, Juliane C., Lehrach, Hans, Sultan, Marc, Shamir, Ron, Sauer, Sascha, Himmelbauer, Heinz, Iraqi, Fuad A., Gat-Viks, Irit
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Genetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050206/
https://ncbi.nlm.nih.gov/pubmed/27761138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2016.00172
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