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Impact of DNMT1 and DNMT3a forebrain knockout on depressive- and anxiety like behavior in mice

DNA methylation has been shown to impact certain forms of synaptic and behavioral plasticity that have been implicated in the development in psychiatric disorders. DNA methylation is catalyzed by DNA methyltransferase (DNMT) enzymes that continue to be expressed in postmitotic neurons in the forebra...

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Detalhes bibliográficos
Publicado no:Neurobiol Learn Mem
Main Authors: Morris, Michael J., Na, Elisa S., Autry, Anita E., Monteggia, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5050143/
https://ncbi.nlm.nih.gov/pubmed/27545441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nlm.2016.08.012
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