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Development and application of a novel model system to study ‘active’ and ‘passive’ tumor targeting
Macromolecular reagents can be targeted to tumors through active and passive mechanisms. ‘Active’ targeting involves moieties, such as receptor ligands, to direct tumor cell binding, while ‘passive’ targeting relies on long reagent circulating half-life, abnormal tumor vasculature, and poor lymphati...
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| Publicado no: | Mol Cancer Ther |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5050124/ https://ncbi.nlm.nih.gov/pubmed/27486224 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-16-0051 |
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