Mechanisms, safety and efficacy of a B cell epitope-based vaccine for immunotherapy of grass pollen allergy

BACKGROUND: We have developed a recombinant B cell epitope-based vaccine (BM32) for allergen-specific immunotherapy (AIT) of grass pollen allergy. The vaccine contains recombinant fusion proteins consisting of allergen-derived peptides and the hepatitis B surface protein domain preS as immunological...

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Vydáno v:EBioMedicine
Hlavní autoři: Zieglmayer, Petra, Focke-Tejkl, Margarete, Schmutz, René, Lemell, Patrick, Zieglmayer, René, Weber, Milena, Kiss, Renata, Blatt, Katharina, Valent, Peter, Stolz, Frank, Huber, Hans, Neubauer, Angela, Knoll, Anette, Horak, Friedrich, Henning, Rainer, Valenta, Rudolf
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5049999/
https://ncbi.nlm.nih.gov/pubmed/27650868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.08.022
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