Adoptively transferred natural killer cells maintain long-term antitumor activity by epigenetic imprinting and CD4(+) T cell help

Natural killer (NK) cell infusions can induce remissions in subsets of patients with different types of cancer. The optimal strategies for NK cell activation prior to infusion are still under debate. There is recent evidence that NK cells can acquire long-term functional competence by preactivation...

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Publicado en:Oncoimmunology
Autores principales: Ni, Jing, Hölsken, Oliver, Miller, Matthias, Hammer, Quirin, Luetke-Eversloh, Merlin, Romagnani, Chiara, Cerwenka, Adelheid
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2016
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Original Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048776/
https://ncbi.nlm.nih.gov/pubmed/27757318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1219009
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