mRNA-transfected dendritic cell vaccine in combination with metronomic cyclophosphamide as treatment for patients with advanced malignant melanoma

Introduction: Vaccination with dendritic cells (DCs) has generally not fulfilled its promise in cancer immunotherapy due to ineffective translation of immune responses into clinical responses. A proposed reason for this is intrinsic immune regulatory mechanisms, such as regulatory T cells (Tregs). A...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Borch, Troels Holz, Engell-Noerregaard, Lotte, Zeeberg Iversen, Trine, Ellebaek, Eva, Met, Özcan, Hansen, Morten, Andersen, Mads Hald, thor Straten, Per, Svane, Inge Marie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
Soggetti:
MIATA Compliant Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048758/
https://ncbi.nlm.nih.gov/pubmed/27757300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1207842
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