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Methylation of SOCS3 is inversely associated with metabolic syndrome in an epigenome-wide association study of obesity

Epigenetic mechanisms, including DNA methylation, mediate the interaction between gene and environment and may play an important role in the obesity epidemic. We assessed the relationship between DNA methylation and obesity in peripheral blood mononuclear cells (PBMCs) at 485,000 CpG sites across th...

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Détails bibliographiques
Publié dans:Epigenetics
Auteurs principaux: Ali, Omar, Cerjak, Diana, Kent, Jack W., James, Roland, Blangero, John, Carless, Melanie A., Zhang, Yi
Format: Artigo
Langue:Inglês
Publié: Taylor & Francis 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048720/
https://ncbi.nlm.nih.gov/pubmed/27564309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2016.1216284
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