Corticotropin-Releasing Hormone Receptor 1 (CRH-R1) Polymorphisms are Associated with Irritable Bowel Syndrome and Acoustic Startle Response

BACKGROUND: Corticotropin-releasing hormone receptor 1 (CRH-R1) in the amygdala and the stria terminalis plays an important role in the activation of central stress circuits. Genetic factors may contribute to the hyperresponsiveness of these circuits in irritable bowel syndrome (IBS). AIMS: To deter...

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Publicado en:Psychoneuroendocrinology
Main Authors: Orand, Alexa, Naliboff, Bruce, Gadd, Malin, Shih, Wendy, Ju, Tiffany, Presson, Angela P., Mayer, Emeran A., Chang, Lin
Formato: Artigo
Idioma:Inglês
Publicado: 2016
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048544/
https://ncbi.nlm.nih.gov/pubmed/27497153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2016.07.204
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