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Hyperglycemia Exacerbates Antiretroviral Drug Combination Induced Blood-Brain Barrier Endothelial Toxicity

In this study, we sought to investigate how concomitant hyperglycemia influences the impact of combination antiretroviral therapy on blood-brain barrier (BBB) endothelial function. Immortalized human brain microvascular endothelial cell line (hCMEC/D3) was exposed to azidothymidine (AZT; a nucleosid...

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Bibliografske podrobnosti
izdano v:Neurotoxicology
Main Authors: Prasad, Shikha, Sajja, Ravi K., Kaisar, Mohammad A., Cucullo, Luca
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048510/
https://ncbi.nlm.nih.gov/pubmed/27345270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2016.06.011
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