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TLR9 mediates S. aureus killing inside osteoblasts via induction of oxidative stress

BACKGROUND: Staphylococcus aureus is the principle causative pathogen of osteomyelitis and implant-associated bone infections. It is able to invade and to proliferate inside osteoblasts thus avoiding antibiotic therapy and the host immune system. Therefore, development of alternative approaches to s...

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Detalhes bibliográficos
Publicado no:BMC Microbiol
Main Authors: Mohamed, Walid, Domann, Eugen, Chakraborty, Trinad, Mannala, Gopala, Lips, Katrin S., Heiss, Christian, Schnettler, Reinhard, Alt, Volker
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048406/
https://ncbi.nlm.nih.gov/pubmed/27716055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-016-0855-8
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