Uranium-loaded apoferritin with antibodies attached: molecular design for uranium neutron-capture therapy.
A method is described to deliver 235U to tumors; the isotope would then be fissioned by incident neutrons, producing localized lethal radiation sufficient for therapy. Apoferritin was loaded with an average of approximately 800 238U atoms per molecule. Stability of the loaded apoferritin in solution...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autor principal: | |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1992
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50484/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1438316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.22.11064 |
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