Antidepressive and BDNF effects of enriched environment treatment across ages in mice lacking BDNF expression through promoter IV

Reduced promoter IV-driven expression of brain-derived neurotrophic factor (BDNF) is implicated in stress and major depression. We previously reported that defective promoter IV (KIV) caused depression-like behavior in young adult mice, which was reversed more effectively by enriched environment tre...

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Detalhes bibliográficos
Publicado no:Transl Psychiatry
Main Authors: Jha, S, Dong, B E, Xue, Y, Delotterie, D F, Vail, M G, Sakata, K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048201/
https://ncbi.nlm.nih.gov/pubmed/27648918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tp.2016.160
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