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Microbial Degradation of Cellular Kinases Impairs Innate Immune Signaling and Paracrine TNFα Responses

The NFκB and MAPK signaling pathways are critical components of innate immunity that orchestrate appropriate immune responses to control and eradicate pathogens. Their activation results in the induction of proinflammatory mediators, such as TNFα a potent bioactive molecule commonly secreted by recr...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Barth, Kenneth, Genco, Caroline Attardo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048168/
https://ncbi.nlm.nih.gov/pubmed/27698456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34656
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