Estimating and testing high-dimensional mediation effects in epigenetic studies

Motivation: High-dimensional DNA methylation markers may mediate pathways linking environmental exposures with health outcomes. However, there is a lack of analytical methods to identify significant mediators for high-dimensional mediation analysis. Results: Based on sure independent screening and m...

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Veröffentlicht in:Bioinformatics
Hauptverfasser: Zhang, Haixiang, Zheng, Yinan, Zhang, Zhou, Gao, Tao, Joyce, Brian, Yoon, Grace, Zhang, Wei, Schwartz, Joel, Just, Allan, Colicino, Elena, Vokonas, Pantel, Zhao, Lihui, Lv, Jinchi, Baccarelli, Andrea, Hou, Lifang, Liu, Lei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2016
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048064/
https://ncbi.nlm.nih.gov/pubmed/27357171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btw351
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