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Characterization of TLR-induced inflammatory responses in COPD and control lung tissue explants

PURPOSE: Viruses are a common cause of exacerbations in chronic obstructive pulmonary disease (COPD). They activate toll-like receptors (TLRs) 3, 7, and 8, leading to a pro-inflammatory response. We have characterized the responses of TLR3 and TLR7/8 in lung tissue explants from COPD patients and co...

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Publicat a:Int J Chron Obstruct Pulmon Dis
Autors principals: Pomerenke, Anna, Lea, Simon R, Herrick, Sarah, Lindsay, Mark A, Singh, Dave
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047739/
https://ncbi.nlm.nih.gov/pubmed/27729782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/COPD.S105156
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