Metal Chelation as a Powerful Strategy to Probe Cellular Circuitry Governing Fungal Drug Resistance and Morphogenesis

Fungal pathogens have evolved diverse strategies to sense host-relevant cues and coordinate cellular responses, which enable virulence and drug resistance. Defining circuitry controlling these traits opens new opportunities for chemical diversity in therapeutics, as the cognate inhibitors are rarely...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Polvi, Elizabeth J., Averette, Anna F., Lee, Soo Chan, Kim, Taeyup, Bahn, Yong-Sun, Veri, Amanda O., Robbins, Nicole, Heitman, Joseph, Cowen, Leah E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047589/
https://ncbi.nlm.nih.gov/pubmed/27695031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006350
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