Human Immunodeficiency Virus-1 Sequence Changes and Drug Resistance Mutation Among Virologic Failures of Lopinavir/Ritonavir Monotherapy: AIDS Clinical Trials Group Protocol A5230

Background. The mechanism of virologic failure (VF) of lopinavir/ritonavir (LPV/r) monotherapy is not well understood. We assessed sequence changes in human immunodeficiency virus-1 reverse-transcriptase (RT) and protease (PR) regions. Methods. Human immunodeficiency virus-1 pol sequences from 34 pa...

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發表在:Open Forum Infect Dis
Main Authors: Vardhanabhuti, Saran, Katzenstein, David, Bartlett, John, Kumarasamy, Nagalingeswaran, Wallis, Carole L.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5047431/
https://ncbi.nlm.nih.gov/pubmed/27704010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ofid/ofw154
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