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Loss of RIG-I leads to a functional replacement with MDA5 in the Chinese tree shrew
The function of the RIG-I-like receptors (RLRs; including RIG-I, MDA5, and LGP2) as key cytoplasmic sensors of viral pathogen-associated molecular patterns (PAMPs) has been subjected to numerous pathogenic challenges and has undergone a dynamic evolution. We found evolutionary evidence that RIG-I wa...
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| Wydane w: | Proc Natl Acad Sci U S A |
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| Główni autorzy: | , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2016
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5047190/ https://ncbi.nlm.nih.gov/pubmed/27621475 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604939113 |
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