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Stac3 has a direct role in skeletal muscle-type excitation–contraction coupling that is disrupted by a myopathy-causing mutation
In skeletal muscle, conformational coupling between Ca(V)1.1 in the plasma membrane and type 1 ryanodine receptor (RyR1) in the sarcoplasmic reticulum (SR) is thought to underlie both excitation–contraction (EC) coupling Ca(2+) release from the SR and retrograde coupling by which RyR1 increases the...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5047181/ https://ncbi.nlm.nih.gov/pubmed/27621462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612441113 |
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