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Molecular determinants of cadherin ideal bond formation: Conformation-dependent unbinding on a multidimensional landscape
Classical cadherin cell–cell adhesion proteins are essential for the formation and maintenance of tissue structures; their primary function is to physically couple neighboring cells and withstand mechanical force. Cadherins from opposing cells bind in two distinct trans conformations: strand-swap di...
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| 發表在: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5047164/ https://ncbi.nlm.nih.gov/pubmed/27621473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604012113 |
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