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An Adaptive Fisher’s Combination Method for Joint Analysis of Multiple Phenotypes in Association Studies

Currently, the analyses of most genome-wide association studies (GWAS) have been performed on a single phenotype. There is increasing evidence showing that pleiotropy is a widespread phenomenon in complex diseases. Therefore, using only one single phenotype may lose statistical power to identify the...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Liang, Xiaoyu, Wang, Zhenchuan, Sha, Qiuying, Zhang, Shuanglin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046106/
https://ncbi.nlm.nih.gov/pubmed/27694844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep34323
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