Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention

Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates that reflect lymphoid neogenesis occurring in tissues at sites of inflammation. They are detected in tumors where they orchestrate local and systemic anti-tumor responses. A correlation has been found between high densities of TLS an...

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Bibliographic Details
Published in:Front Immunol
Main Authors: Sautès-Fridman, Catherine, Lawand, Myriam, Giraldo, Nicolas A., Kaplon, Hélène, Germain, Claire, Fridman, Wolf Herman, Dieu-Nosjean, Marie-Caroline
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2016
Subjects:
Immunology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5046074/
https://ncbi.nlm.nih.gov/pubmed/27752258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00407
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