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Population pharmacokinetic and pharmacodynamic analyses of safinamide in subjects with Parkinson's disease
Safinamide is an orally administered α‐aminoamide derivative with both dopaminergic and non‐dopaminergic properties. Nonlinear mixed effects models for population pharmacokinetic (PK) and pharmacokinetic–pharmacodynamic (PKPD) analyses were developed using records from, respectively, 623 and 668 pat...
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Gepubliceerd in: | Pharmacol Res Perspect |
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Hoofdauteurs: | , , , , , |
Formaat: | Artigo |
Taal: | Inglês |
Gepubliceerd in: |
John Wiley and Sons Inc.
2016
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Onderwerpen: | |
Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5045937/ https://ncbi.nlm.nih.gov/pubmed/27713822 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.251 |
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